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产品描述
包装
5, 25 mg in glass bottle
Biochem/physiol Actions
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.
Features and Benefits
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
性质
| Related Categories | A-AM, AMP-Activated Protein Kinase (AMPK), AMPK通路抑制剂和激活剂, Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, |
| InChI Key | RTRQQBHATOEIAF-UUOKFMHZSA-N |
| assay | ≥98% (HPLC) |
| form | powder |
| color | tan |
| mp | 214-215 °C |
| solubility | H2O: >7 mg/mL |
| shipped in | dry ice |
| storage temp. | −20°C |
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